Natural Factors Chromium Vanadium works synergistically to maintain a healthy body. They are involved in glucose metabolism and needed for healthy insulin production support healthy blood glucose regulation. Chromium is a component of a molecule called Glucose Tolerance Factor (GTF) that regulates blood sugar levels in the body. The hormone insulin will not work without dietary chromium. When we get enough chromium in our diets, our sensitivity to insulin is improved and blood sugar levels are normally regulated. Vanadium is an ultra-trace mineral found in our body and in a variety of foods. Vanadium works with chromium to support healthy blood sugar levels. Insulin resistance may occur as people age, as their cell receptors sit's are not as responsive to their own production of insulin, causing irregular insulin and blood glucose levels.